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Use code block not rmarkdown formatting
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llrs
llrs
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You could try it with sed.
Replace all lower-case chars with - in lines not starting with >:

sed -e '/^>/!s/[a-z]/-/g' in.fa

You could try it with sed.
Replace all lower-case chars with - in lines not starting with >:

sed -e '/^>/!s/[a-z]/-/g' in.fa

You could try it with sed.
Replace all lower-case chars with - in lines not starting with >:

sed -e '/^>/!s/[a-z]/-/g' in.fa
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Peter Menzel
Peter Menzel
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You could try it with sed.
Replace all lower-case chars with - in lines not starting with >:

sed -e '/^>/!s/[a-z]/-/g' in.fa