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Jun 18, 2020 at 8:30 history edited CommunityBot
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Jun 9, 2017 at 1:57 comment added gringer That does happen to some degree, but the Rosetta [computer] model doesn't do this. A whole bunch of odd things happen with protein folding. For example, there are chaperone proteins that encourage folding in a particular fashion to get through low-energy humps to reach a higher energy state. The foldit researchers have found a way to model chaperones using a technique called "humans".
Jun 8, 2017 at 22:24 comment added J.J wow that's surprising. I would have expected the protein to start folding as soon as one end of it is able to, which is probably the first end to leave the ribosome. The last amino acid probably hasn't even been attached yet, let alone available for moving and calculating the energy :)
Jun 8, 2017 at 15:00 history answered gringer CC BY-SA 3.0