How I deal with this expression set?

I have a gene expression raw counts like below for 16 patients

         A  B    C      D   E   F
A2M     511 1623 665    208 553 469
AADAT   34  137 372     7   52  124
ABCB1   119 114 123    22   25  89
ABCB11  27  186 200    27   30  49
ABCC2   1   10  21     1    8   3


For each patients I also have some characteristics

Patients                          IC          TCs
A1                                3            3
B1                                2            0
C1                                2            0
D1                                0            0


I want to find genes differential expressed in these patients regarding these characteristics but I don't know how to do that