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I would like to ask if anyone knows or has experience in representing BigWig signals in a circular plot? I mean like IGV but in circular plot not linear. Or any library that can be used in plotting BigWig signals especially in Javascript?

I appreciate any suggestion, Thank you.

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circosJS should probably work well, based on your requirements: https://github.com/nicgirault/circosJS

I posted a short Observable notebook that shows what calls could be used to bring data from remote bigWig files into a circosJS plot:

https://observablehq.com/@alexpreynolds/rendering-bigwig-file-data-in-a-circular-representation

It is less intended as an explicit how-to in Javascript, than as a starting point for the end user with some of the function calls and data scale issues involved. Hopefully it can be useful to the reader for exploratory purposes.

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  • $\begingroup$ Does it take bigwig file without any conversion to tabulated format? $\endgroup$
    – Abed Kurdi
    Apr 15 '20 at 7:46
  • $\begingroup$ Doesn't look like it, but you could probably use github.com/GMOD/bbi-js as a file parser, get the data you need asynchronously, and feed it to circosJS to render. $\endgroup$ Apr 15 '20 at 7:59
  • $\begingroup$ Thank you very much on your suggestion, I will give it a try and see if it works. $\endgroup$
    – Abed Kurdi
    Apr 19 '20 at 17:19

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