I'm doing a project for DNA archival storage systems
Is there an open-source dataset used as ground truth for clustering?
A file containing the ground truth strand sequences, which have been synthesized:
Dataset 1 st1: ATGCGTGC st2: GCTGATTC st3: AATGCGTT
And another file containing the sequenced strands, where for each original strand we read multiple 'erroneous' strands:
Dataset 2 st1 cluster: ATTCTTGC TTGCGTGC ATGCGTGT st2 cluster: GCTGATTC GATGAATC GCAGATTA st3 cluster: AATGCGTT ATTGCTTT AATATGTT
Where the clusters can then be used for a consensus alignment algorithm.
What I'm aiming to do is to use an algorithm to learn a mapping from dataset1 to dataset2, so that for an arbitrary strand (stx) I can generate a corresponding 'erroneous' cluster (stx cluster)
The two datasets should come from a real synthesis and sequencing pipeline.