# Functional Annotation vs Functional Enrichment--which one should I use for Network Analysis?

I am currently working on a network pharmacology project where I am supposed to find out the possible diseases our drug might have an effect on. I am not a bioinformatics student, so my knowledge in the subject matter is very limited. I have all the targets and I am supposed to get the pathways associated with the targets. I used STRING for the purpose.

• I got both KEGG functional annotation and enrichment for my list of targets.
• I have to build a two-mode network

Question I am not very clear about

• the difference between enrichment and functional annotation and
• which data should be used for the next step.
• If you can add more detail that might help, such as the pathway(s) your STRING analysis indicates. Your question appears vague for the decision you have and it is not clear why you don't use both for two different network analyses
– M__
Nov 22, 2020 at 9:44