I am interested in detecting allelic imbalance for a credible set of SNPs. Currently, I am looking for some packages, hopefully, for Python, that can assist with this. I am aware of this R package, https://bioconductor.org/packages/3.13/bioc/html/AllelicImbalance.html, but I am hoping someone knows of a similar Python library.


  • $\begingroup$ You're comparing availability on Bioconductor to availability on Python. BioC is specializing on biological software, which Python does not (or at least doesn't have an equivalent community). $\endgroup$
    – Ram RS
    Nov 25 '20 at 20:20
  • $\begingroup$ Why not just use R? Jumping between that and python is the norm. $\endgroup$
    – Devon Ryan
    Nov 25 '20 at 22:11
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    $\begingroup$ What do you mean by "allelic imbalance". This maybe a term used in RNAseq because everyone seems to understand it, but this is not a term used in population genetics. $\endgroup$
    – M__
    Nov 26 '20 at 1:51
  • $\begingroup$ @RamRS, I am more familiar with Python, and dont have alot of experience with R. With that being said, I should probably familiarize myself with R going forward. $\endgroup$
    – Krizbomb
    Nov 30 '20 at 13:52
  • $\begingroup$ It's not about the language itself, @Krizbomb. Python doesn't have a BioC equivalent, AFAIK. $\endgroup$
    – Ram RS
    Nov 30 '20 at 17:40

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