We had same set of sample ran on nanopore platform twice.
The issue on hand is.
First run was done it was nearly done but the power went off. Second run was done completely with enough sequencing depth.
Now the question I ran the analysis with the second set which was complete that set of result I have. But so far I have't ran the first part.
Question1 : if I run the first part do i get major differences? in the result
Question2 : would it be advisable to merge both run since they are now can be called as twi different batches plus would be bring drastic changes in the output ? And in terms of tool for merging I googled which shows poretools.