1
$\begingroup$

I came across this paper as one of the examples from this paper, this one

Figure 2. Host Protein Alterations in Infected iAT2s

(B) Dysregulated (FDR < 0.05) functional modules, including (bottom) U7 snRNA and HDAC-associated complexes.

So how should be the data frame should be for my clustering and visualization. If i have to replicate the same for lets say 4 different time point how to do that.What i have done so far.

I have 4 condition C1,C2,C3,C4. I did pairwise comparison between C1vC2, C2vC3 , C3vC4.

So now I did pathway enrichment with the comparison above. I have for C1vC2, then C2vC3 and C3vC4.

Now I how to proceed what they have shown here. Do i intersect all the pathway that is common in all three? such that based on the any metric that is present I can cluster and show the differences or is there any simpler way.

enter image description here

$\endgroup$

0

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service and acknowledge that you have read and understand our privacy policy and code of conduct.

Browse other questions tagged or ask your own question.