I'm trying to convert mouse genes from PTX data to human genes in order to do a comparison with patient data to see what genes are being conserved. I'm using this file for the orthologs. http://www.informatics.jax.org/downloads/reports/HOM_MouseHumanSequence.rpt
I read the table with:
gene_conversion <- read.table("HOM_MouseHumanSequence.rpt.txt", sep="\t", header=T, fill=T)
I have subsetted the mouse genes from the PTX seurat object to only include the mouse genes with:
mouse_only <- subset(scData, features = mouse_1) head(rownames(mouse_only))  "Xkr4" "Gm37180" "Gm37363" "Gm19938" "Sox17" "Gm6085"
Now I'm not sure how to convert the mouse genes in my mouse-only seurat object to match the human genes in the file.
Any help would be greatly appreciated.