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Some websites mention amino acid mutations as ORF1ab, most however use ORF1a/b instead.

So how can I translate from one to the other? What do I need to subtract from say ORF1ab:4588I to get the corresponding N in ORF1b:<N>I?

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2 Answers 2

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ORF1ab:4588I corresponds to ORF1b:187I so one needs to subtract 4401 to go from 1ab to 1b and add 4401 to go the other way.

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    $\begingroup$ Just for clarification: 1a or 1b? You reference 1b in the question but answer with 1a. $\endgroup$ Feb 28, 2022 at 6:49
  • $\begingroup$ You're right, I fixed it, thanks! $\endgroup$ Feb 28, 2022 at 13:33
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There is now an Open Source online tool that does the conversion, Codon2Nucleotide by Theo Sanderson.

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