I have been working on FindMarkers function for identifying significant genes in the cluster. But some Significant genes have very low p values, so they are returned as 0 in the output.Any value less than the .machine$double.xmin limit on R(that is 1e-305). So this output cannot be used for further plots like Volcano plots for visualization. Any solution to get p values for all the genes?
cd4.markers <- FindMarkers(sc.combined, ident.1 = "CD4+ T cell", min.pct = 0.25)