I have a reference sequence of amino acids that I compare other sequences to using
Bio.pairwise2.align.globalmx of Biopython package (one to many compare - one by one [is there a better way?])
It's works fine but only returns strings of the alignment with very little metadata.
Now I want to extract the indices of the amino acids that are different than the reference sequence and plot it in some kind of histogram according to protein features:
- pos 1-36: 3 mutations.
- pos 37-202: 4 mutations.
- pos 203: 1 mutation
- pos 204-660: 0 mutations
Is there any builtin package to do so?
How can I get the data of diff between 2 sequences in python? I mean which AA changed to which AA and at each position.
Bio.pairwise2.align.globalmx returns some data structures of strings (see below) that can be printed but does not contain the locations in a convenient way.
LLGHKVNPFKALYNRIDMK-QVEALVEASKEE |||||||||||||||||||||||||||||||| LLGHKVNPFKALYNRIDM-RQVEALVEASKEE