3
$\begingroup$

I'm trying to retrieve the most expressed genes from a cell line from the NCI-60, lets say cell line NCI-H23, but I'm not sure where to find the gene expression data. My main goal is to create a network using that data and iRefIndex to be loaded into Cytoscape. Does anyone know where I can find the correct data or guide me in the right direction?

$\endgroup$
2
$\begingroup$

CellMiner portal has plenty of data about NCI-60 cell lines, inclusive microarray gene-expression.

Also, NCI-60 is a subset of the ~1000 cell lines covered by the GDSC project for which you have multiple types of measurements (e.g. copy-number, mutation, gene-expression).

$\endgroup$
2
$\begingroup$

Cosmic Cell Lines Project provides gene expression data for 1000+ cell lines (including NCI-60 panel together with NCI-H23 cell line). For each gene in a cell line, you can get Z-score and over/under-expression status calculated across all tumor samples diploid for that gene.

$\endgroup$

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.