I'd like to output a figure in +/-1kb around a center using computeMatrix as following command:
computeMatrix reference-point -S data.bw -R centers.bed -a 1000 -b 1000 -bs=10 -out newdata10.gz --referencePoint center
The bed file is like:
chr1 100 101
If I change
-bs=1, two outputs of the same input newdata10.gz are quite different. Which's correct with my commands? Maybe I don't understand the meaning of binsize option.