I have a Mac Book Pro and I am about to start a sequencing run on the MinION. MinKNOW is going to be running for 2 days. Can I use my computer during sequencing? Can I browse the web and use Excel, etc? I am not speaking about running a parallelised genome assembly on all my cores using my entire RAM but more mundane activities, like checking my emails or taking notes. Furthermore, can I lock my screen using Control + Shift + OFF without negatively affecting the sequencing?

  • $\begingroup$ By locking do you include suspending the machine or not? $\endgroup$ – llrs Feb 21 '18 at 21:51

Yes, that should be fine, especially if basecalling is disabled. Locking a screen should be fine as well.

I prefer to do basecalling after a run anyway, because there's a chance that it could chew up too much processor time and result in lots of skipped reads.


Since biological samples and reagents cost time and money, I wouldn't push it too much. Checking your email would be fine, but I wouldn't be browsing the web (besides gmail/calendar) in case a plug-in (e.g. flash), bad javascript, etc. causes any trouble.

I'd disable any auto-updates too.

Locking the screen would be fine.

Personally, I'd buy a cheap chromebook and let the Mac work.


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.