I have a Mac Book Pro and I am about to start a sequencing run on the MinION. MinKNOW is going to be running for 2 days. Can I use my computer during sequencing? Can I browse the web and use Excel, etc? I am not speaking about running a parallelised genome assembly on all my cores using my entire RAM but more mundane activities, like checking my emails or taking notes. Furthermore, can I lock my screen using Control + Shift + OFF without negatively affecting the sequencing?
Yes, that should be fine, especially if basecalling is disabled. Locking a screen should be fine as well.
I prefer to do basecalling after a run anyway, because there's a chance that it could chew up too much processor time and result in lots of skipped reads.
I'd disable any auto-updates too.
Locking the screen would be fine.
Personally, I'd buy a cheap chromebook and let the Mac work.