What is the difference between C383S and C383A? For C383S, does it mean Cysteine(C) position 383 in the sequence and its next amino acid connect to it is Serine(S)?


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This means that at position 383 the Cysteine(C) is mutated to a Serine(S). Depending on the organism and gene usually the mutation notation is linked to a specific transcript since the position could vary depending on transcript splicing.

  • $\begingroup$ How about Pro136? Does it means Proline is deleted at position 136? $\endgroup$ Commented Apr 4, 2019 at 1:58

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