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I'm using snpEff to annotate some VCFs and getting some spurious annotations that don't have transcript ids. Some of these annotations have a gene name followed by ampersand such as PCDHB@ and I'm not finding any explanation in the docs.

Any idea what this refers to? Entire gene family?

Thanks.

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The @ at the end of a name denotes a "gene cluster in chromosome region". This is mentioned in the official HUGO nomenclature guidelines in the "Characters reserved for specific usage" section:

[HUGO reserved characters table

It's also mentioned in the GeneCards documentation:

enter image description here

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  • $\begingroup$ Very informative. Thanks! $\endgroup$
    – 111
    Jun 10, 2019 at 4:27

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