What is the difference between these two databases?

ftp://ftp.ncbi.nlm.nih.gov/blast/db/ and ftp://ftp.ncbi.nih.gov/genbank/

I understand that BLAST database has both nt for nucleotide and np for protein. But genbank is also for genomic database. So what is the difference between nt and Genbank databases?


  • 1
    $\begingroup$ They are the same data, but the interegation of the database is very different. Blast uses a similarity algorithm but Genbank uses record referencing. It is better to limit the quesiton towards a specific biological problem for a more detailed answer $\endgroup$
    – M__
    Sep 10, 2019 at 20:52

1 Answer 1


I think the BLAST folder contains pre-formatted databases for BLAST whereas the GenBank folder contains sequences.


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.