Questions tagged [bgzip]

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concatenating windowed VCF files, but quickly?

I am calling variants from WGS for a genetically diverse species which, with my sample size, produces a (bgzipped) VCF of around 500G. I am using a nextflow pipeline to chunk up the genome, call ...
2 votes
1 answer
237 views

How to obtain file offsets corresponding to range query in block-gzipped file

How can we retrieve the file offsets of the zipped-chunks in a block-gzipped file that contain records for a region/window of interest (e.g. Chr01:100-Chr02:145)? It seems like the CLI of ...
1 vote
0 answers
323 views

How to troubleshoot access to tabix file via http or https?

I have some BED files that I have compressed with bgzip and indexed with tabix. I am using version ...