All Questions
9 questions
1
vote
0
answers
21
views
How can I associate centrality score of genes(vertices) in a GRN with the probabilistic model in terms of cause and effect?
I'm learning to build Bayesian Network Based Modeling of Gene Regulatory Network of Cancerous Cellular Cells. So far, I have learned to form a Bayesian Network based on nature of genes(i.e Functional ...
1
vote
1
answer
713
views
Clustering of gene co-expression network by igraph R package
I have constructed a gene co-expression network from RNA-seq data. The network has more than 10000 nodes and more than 1 million edges.
The network file as an edge list format of memory around 1gb ...
0
votes
1
answer
306
views
How do I get the adjacency matrix from gene similarity network?
I am exploring application of Graph convolution network on gene similarity network. I am trying to explore
genemania.org and https://string-db.org/
Please let me know where can I find the data for my ...
0
votes
1
answer
72
views
How to create a graph of multi column gene dataset?
well, I'm new to Bio. what I'm going to do is create a network/graph of a dataset related to the genes I think. here's the sample of the nodes dataset with CSV format named lung-nodes :
and this is ...
7
votes
2
answers
201
views
Are gene names same across species?
I have a bunch of gene names of Apis mellifera (specifically 194). I used these gene names as an input on STRING database to create a network for Drosophila melanogaster. 54 of those genes were also ...
3
votes
1
answer
63
views
How to read gene regulatory network edge list files?
The following is an excerpt from an edge list file from the Gene Regulatory Database, YeastNet v3
...
2
votes
0
answers
95
views
Locate KEGG/Reactome pathways in user defined network
I am working on big networks of genes. I want to locate KEGG/Reactome pathways in my network. I have already tried cytoKegg and ReactomeFI (Plugins of Cytoscape), they only give me a list of Pathways ...
1
vote
0
answers
82
views
Help with generating network from gene expression data
I'm struggling to figure out how to go from gene expression data to be able to create a network out of the most expressed genes in a cell line. Ok, I have developed an application for Cytoscape where ...
10
votes
4
answers
890
views
How can I build a protein network pathway from a gene expression quantification file?
Assume I have found the top 0.01% most frequent genes from a gene expression file.
Let's say, these are 10 genes and I want to study the protein protein interactions, the protein network and pathway....