Questions tagged [impute2]
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4
questions
1
vote
2answers
79 views
1000 genomes missing SNPs on chr X in GRCh38
I am trying to get a reference together for imputation using the 1000 genomes data set. The GRCh38 version of the data set was made available earlier this year, but seems to be missing a significant ...
3
votes
1answer
62 views
IMPUTE2 missing filter option
I went through the manuals and can't find the meaning of the below flag:
-filt_rules_l 'filter==0'
Here is the link to manual for this flag: filt_rules_l
Can ...
8
votes
3answers
2k views
How to convert the .vcf (imputed) file with GT:GP format to GT:DS?
I have the genotyped data from impute2 output in .gen format (imputed to 1000G P3). The file has genotype posterior probabilities (GP:3 values per variant). I have converted .gen to .vcf using qctools ...
7
votes
1answer
156 views
Imputing missing genotypes from separate genotyping panels
What is the current standard for imputing missing genotypes between two genotyping panels? I have two populations genotyped using two different panels (A & B), and I would like to impute all the ...
