Questions tagged [linear-regression]

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1answer
96 views

Doing plot with this data

I have normalized expression values of some genes in some patients and the how many days they have survived from their diagnosis with cancer like below EDITED I have taken mean of the expression ...
0
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1answer
47 views

Investigate the effect of street-light regime on insects

I need advice on a suitable analysis of a dataset that has an awkward design - because we investigate a real-world situation -we have two sites (A,B) where we can conduct the research. The hypothesis ...
2
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1answer
39 views

How are residuals used as new phenotype?

I'm a novice trying to wrap my head around with fancy jargons. If I search residual, I understand that it represents the difference between the observed value of the dependent variable (y) and the ...
3
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0answers
82 views

Several models identify different which genes are significant

I want to find some good predictors (genes). This is my data, log transformed RNA-seq: ...
5
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3answers
594 views

Regressing out unwanted sources of variation in single cell RNA-seq data

I have a dataset of single cell count data and I want to regress out the variation caused by the number of UMI's and the percentage of mitochondrial genes. I know that count data is discrete data, ...
5
votes
1answer
172 views

Scaling by linear regression against the number of reads

I am trying to build the preprocessing pipeline presented in The Tabula Muris Consortium et al. (pp). It is a pipeline to preprocess single-cell sequencing data. There is one step that is not clear: ...