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Questions tagged [literature-search]

Use this tag when looking for a reference of a method, data, result or discussion.

3
votes
1answer
41 views

Error correction within the long read

I am going to get some data from plasmid sequencing to identify SNPs on the plasmids. What is done in the lab is the following: The plasmids are purified by size. We amplify the plasmids using the ...
0
votes
0answers
26 views

Predicting of predispositions [closed]

Is it possible to predict predispositions of the child, based on only two parental DNA? What algorithms / technologies are used for this?
0
votes
1answer
18 views

Build a Pubmed query given long gene list

I would like to search the literature using the Pubmed search engine for a set of genes that are associated with a brain region of interest. Unfortunately, there are a lot of them. It's possible there ...
0
votes
1answer
33 views

How to calculate Moreau-Broto autocorrelation, Moran autocorrelation, Geary autocorrelation from protein (amino acid) sequences?

I want to code Moreau-Broto autocorrelation, Moran autocorrelation, Geary autocorrelation in Python 3.6 from the scratch for amino acid sequences without using any package. Unfortunately, I have not ...
0
votes
0answers
17 views

What is the most efficient method to identify a protein that has undergone post-translational modifications by an enzyme?

I am in the process of conducting research on a wide array of proteins that are all post-translationally modified by the human enzyme GSK-3beta. What is the best to show (using peer-reviewed research ...
5
votes
2answers
169 views

Books on bioinformatics algorithms

I'm looking for a book about bioinformatics algorithms, such as alignment, BLAST search, and variant calling. I'm hoping reading about this subject will give me a deeper understanding of the ...
5
votes
2answers
160 views

What is the distribution of indel sizes in a healthy human genome? of insertion:deletion ratios?

My understanding is that indels are from 1bp to 10Kb, and a healthy genome has ~400K-500K Indels. Surely most of these are small. What is the distribution of insertion sizes in a healthy human ...
-5
votes
1answer
96 views

Influential papers in bioinformatics [closed]

As a newcomer, what are some influential research papers published in the past few years that I should read to catch up in the field? Edit: @Devon Ryan answered it perfectly. I tried a google search ...