Questions tagged [point-mutation]

Single mutation in the DNA or RNA for RNA viruses, also known as single nucleotide polymorphism (SNPs)

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Site Mutations in a 3D protein structure to locate the core of mutations

I have a pdb file for a protein (3D structure predicted by a tool) and around hundreds of known point mutations in the protein. I want to visualize the protein with all the mutations to see the hub of ...
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How to introduce point mutations in a protein structure?

I want to introduce point mutations to a protein PDB file and automatically predict the 3D coordinates of a new amino acid residue in the mutated protein. I used interactive Schrodinger's Maestro tool ...
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How to select point mutations from MAF file

I am using a mutation MAF file from GDC. I want to select for point mutations, therefore I selected Variant_Classification equal to ...