Questions tagged [secondary-structure]
The secondary-structure tag has no usage guidance.
19 questions
0
votes
0
answers
86
views
How can I visualize protein secondary structure?
I'm currently working on a secondary structure prediction model and I'd like to visualize what will be predicted , the format of secondary structure sequence is consisted of 8 labels:
G: 3-turn helix ...
- 21
2
votes
1
answer
90
views
Why do we need seondary structure detection algorithms?
There are many secondary structure prediction and assignment algorithms (e.g., DSSP, STRIDE, etc.) available.
On the other hand, I see that PDB files have secondary structure information available in ...
- 845
4
votes
0
answers
106
views
Why are DSSP and STRIDE considered reference algorithms, and why do people continue to use them?
I am working on globular protein secondary structure assignments. The purpose of my project is to design an improved algorithm for secondary structure assignment.
I know two tools: ...
- 845
3
votes
1
answer
52
views
How can I detect secondary structures in a protein using a hydrogen bond detection algorithm?
Suppose I have a protein chain. And I have a hydrogen bond detection algorithm that can detect hydrogen bonds in a protein chain. Say, the name of the algorithm is HBDA algorithm.
How can I detect ...
- 845
2
votes
0
answers
18
views
Is there any python module to assign secondary structures which includes both Polyprolene region as well as individual strand as well?
I wanted to assign secondary structure to set of pdb files. However, DSSP and STRIDE cannot assign for single peptides if it is falling inside single long beta strand or polyprolene region as it does ...
3
votes
0
answers
24
views
which secondary structure assignment algorithm is used by PDB?
older releases of PDB used to specify DSSP as the 2ary structure assignment algorithm used in PDB, right now no algorithm is explicitly stated. Where can I find a reference for it in the database?
- 31
0
votes
1
answer
75
views
Is there a software that extract molecular descriptors of single stranded RNAs secondary structure from dot bracket notation in nucleotide resolution?
I want to generate descriptors from dot bracket notations of single stranded RNA/DNA secondary structures. So far i have come across this paper:https://journals.plos.org/plosone/article?id=10.1371/...
- 33
4
votes
1
answer
204
views
RNA folding at specific temperature with ViennaRNA in python
I am trying to get dot-bracket-notations of single stranded RNA via the ViennaRNA python package (https://pypi.org/project/ViennaRNA/) at different temperatures. I have read in the docs (https://www....
- 41
1
vote
1
answer
479
views
Visualize RNA co-folded secondary structure with Python
I would like to visualize the secondary structure of co-folded RNA strands in Python, preferably in a Jupyter notebook.
What are the recommended tools? Can anyone provide an example?
- 111
2
votes
2
answers
68
views
Sequence format: grouping sequences within a flat file
Is there a sequence format allowing multiple sequences to be grouped across a flat file? The specific application is stacking separate nucleotide sequences against a given RNA secondary structure.
To ...
M__♦
- 13k
2
votes
0
answers
82
views
Program for SOV calculation
Are there any programs (web server or installable) out there to calculate segment overlap score (SOV) for protein secondary structures?
Thanks
- 95
2
votes
1
answer
109
views
Chou-Fasman Method Overlapping Regions Problem - Secondary Structure Prediction
According to the Chou-Fasman method, when there is an overlapping region on the amino acid sequence, we compare the scores of alpha-helix and beta-sheet and chose the highest one.
Let's say I have ...
- 21
0
votes
2
answers
881
views
Unable to execute DSSP algorithm from BioPython
I have the following settings in PyCharm:
BioPython is properly installed:
dssp_test.py
...
- 845
3
votes
2
answers
260
views
What is protein secondary structure assignment?
I am absolutely new to Structural Bioinformatics (I only started last week). I am working on the secondary structure assignment/prediction (actually I am not sure) of proteins using ML.
When it comes ...
- 845
1
vote
1
answer
126
views
Searching for proteins by primary and secondary structure
I need to find peptides/proteins with a certain sequence of amino acids in a certain type of secondary structure. For example, "ALA PHE GLY" in alpha-helix. Is there any tool that does that?
- 123
3
votes
1
answer
135
views
protein secondary structure matching/comparison scoring
I want to compare two secondary structures of aligned proteins. I do not know exactly how to do it well.
Example:
...
- 147
1
vote
2
answers
2k
views
How to plot a 2D RNA structure in python using dot-bracket input?
I need some help with forgi library for visualisation of RNA secondary structure.
I have an RNA sequence and dot-bracket notation of the secondary structure and I would like to plot 2D graph like ...
1
vote
1
answer
176
views
Which is the amino acids classification when analyzing the solvent accessibility of a protein?
I came across an article which has defined 3 categories: Buried [A, L, F, C, G, I, V, W], Exposed [ R, K, Q, E, N, D] and Intermediate [M, S, P, T, H, Y] when analyzing the solvent accessibility of a ...
- 123
1
vote
0
answers
40
views
Which secondary structure prediction algorithms don't query the PDB/DSSP for known homologous sequences?
There are several secondary structure prediction algorithms. I am interested in the algorithms which predict secondary structure without accessing the PDB to cheat by using the DSSP or STRIDE entry ...
- 527