I have `RNA-seq` for two groups of patients: `Responders` to chemotherapy (n=9) versus `non-responders` to chemotherapy (n=24)

I have done `DESeq2` and obtain `fold change of responders versus non-responders` in which `positive fold change` means `down-regulation in responders` (if I am not wrong)

    > head(df)
        gene       FC
    1 286499 7.116071
    2 260436 6.691189
    3   2267 5.751322
    4   5968 5.522079
    5   4103 5.328008
    6 442709 5.036087
    > 

I have done `GSEA` in `pre-ranked` way

 got this plot for `KRAS pathway`

[![enter image description here][1]][1]


  [1]: https://i.sstatic.net/mwPGW.png

I interpret this as; `KRAS pathway` in being `down regulated` in `responders`

Am I right?

Please correct me