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Deseq2 is an R package for analyzing RNA sequencing data

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DESeq2 for large number of samples takes too much RAM

I am trying to run a very large number of transposase-accessible chromatin (ATAC)-seq samples through DESeq2 to find peaks of differential chromatin accessible across my study genome. … Does anyone have an alternative strategy to use DESeq2 on a very large dataset? Should I look into doing a Wilcox-rank test myself? Thanks. …
Shashank Nagaraja's user avatar