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Nucleotide base changes in the genome from its parental copy which for eukaryotes or bacteria is DNA

1
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You can read in a excel file using readxl library(readxl) library(dplyr) df <- read_excel(FILENAME) To get the number of mutations per gene: df %>% group_by(`Gene name`) %>% summarise(num_mutations … =n()) If you want to know if there are mutations in a particular gene: df %>% filter(`Gene name` == QUERY) …
answered May 18 '18 by heathobrien
2
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Without control data from your subjects, I don't think there's really no way to distinguish somatic mutations from germ-line mutations. … The best you can do is to screen out common variants, which are germ-line mutations that are shared by large numbers of individuals using the population frequencies from something like the Exome Aggregation …
answered Apr 16 '18 by heathobrien