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An abnormal growth of cells that can threaten an individual's life. Cancerous cells are very proliferative and can spread to other parts of the body, creating metastases.

1
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Answer from @fabio-marroni, converted from comment: WARNING! Self-promotion! We published a freely-available tool for detection of LOH (and also redeuction fo homozygosity). Here you find the link to …
answered May 12 '21 by gringer
2
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The trouble with looking for cancer-associated variants is that it can be difficult to tease out spurious effects (e.g. ethnicity) from causative variants. … If you're interested in what genes are implicated in most types of cancer, the annotations for the NanoString panels are quite good: cancer pathways cancer progression The "Support documents" section …
answered Jun 15 '17 by gringer
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I'm not familiar with this file structure, but have you looked at the forum post about relative copy number linked to in the FAQ? Since we do not have matched normals, the output is a “copy ratio” or …
answered Jan 22 by gringer
3
votes
This existed as a closed silo, at least in 2015. Qiagen has a team of hired students and Post-Docs for collating research papers into their Knowledge Base, an extensive database that is integrated int …
answered Jul 9 '17 by gringer
5
votes
There was a Structural Variant breakout session at the London Calling conference this year. Unfortunately I didn't attend that session, but MinION community members have access to Constance Donnell's …
answered Jun 4 '17 by gringer
0
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Just in case an R solution is acceptable as well, this should be fairly robust code because it properly parses the TSV files and matches up column names: #!/usr/bin/env Rscript library(tidyverse) rea …
answered Aug 9 '21 by gringer