3 votes

Population Allele Frequency

I don't know specifically about the UKBB RAP, however, Population Allele Count is the count of that specific allele genotyped in the population in question. In this case, it most likely refers to the ...
Yossi Farjoun's user avatar
3 votes

Variant allele frequency versus population frequency

gnomAD provides a global Allele Frequency as well as AF values for most subsets. gnomAD does not provide individual genotypes (as far as I know), so calculating custom AF for non-precomputed subsets ...
Ram RS's user avatar
  • 2,289
1 vote

What is the meaning of "Filtering allele frequency" in the gnomAD database?

My understanding is from Whiffin et al. 2017. Imagine a dominant mendelian disease A with complete penetrance, caused only by one allele, which is currently unknown. In your search for that unknown ...
ning's user avatar
  • 141

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