Unable to install an R Bioconductor package on Apple M1/M2
The easiest solution is to install the x86 version of R in your M1/M2 Mac here. It will be then emulated by the Rosetta. After that you will have no problems with Bioconductor packages
Where to find asymmetric nucleotide substitution matrix with IUPAC encodings?
Additional answer on asymetric IUPAC score matrix. To get the scores with an asymentric score matrix. This is also implemented in the Bioconductor package MSA2dist (https://www.bioconductor.org/...
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