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8 votes

relation between Illumina sequencing primer and viral sequences

You'll unfortunately find adapter sequences contaminating a lot of entries in Genbank. In short, the sequence is most likely either an unassembled fragment where the input into the assembly step hadn'...
Devon Ryan's user avatar
  • 19.7k
3 votes

Virus genome: protein inside another protein

Note that the protein sequence of ORF8b is not contained within the protein sequence of protein N. That means that they are translated from different frames (though they are in the same orientation). ...
Maximilian Press's user avatar
2 votes
Accepted

COVID-19 GWAS: what is a cross-replicating association?

Replication in GWAS is an analytical term, approximating to 'robustness'. It is not biological phenomenon of a genome replicating. What the authors are saying is these genes associate with an allelic ...
M__'s user avatar
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2 votes
Accepted

Human Herpes Virus, fusion motif in protein vs. SARS-CoV-2?

I can answer that ... I'm afraid no. What you are asking is whether there is any similarity in their cellular receptor binding or "fusion loops" because the motifs look a bit similar. These ...
M__'s user avatar
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2 votes
Accepted

Prediction model for spread of coronavirus

The original R0 calculation was developed in the early 1900s to model malaria transmission and is known as the Ross-MacDonald model so your idea is over 100 years old. The model was very famous for ...
M__'s user avatar
  • 12.6k
2 votes

Virus genome: protein inside another protein

Essentially @MaximilianPress hit the nail on the head. sgRNA is a major feature of SARS-CoV-2. This is where the 5' UTR is spliced at numerous locations in the genome, such that although it is a ...
M__'s user avatar
  • 12.6k
1 vote

Why ORF13 and ORF14 of Bat Sars coronavirus Rp3 have no corrispondence in Sars2?

The virus Rp3 stands for Rhi pea isolated in China in 2004. The trees is here and groups with the Bulgarian sarbecoviruses and is closely related to the African sarbecoviruses. Thus although it is a ...
M__'s user avatar
  • 12.6k

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