New answers tagged differential-expression
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scRNA-Seq pseudobulk for marker detection
If you want a statistical reason not to use pseudobulk to do DE for marker finding, I think it is the same reason not to use any DE method for marker finding: the double dipping problem (see Gao and ...
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Can I perform Expression Analysis on this 10x dataset?
Typically what this PMBC RNA-seq data set would be used for is for a control against individuals who would exhibit a pronounced cellular immune response. For example, following a COVID19 infection the ...
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