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5 votes

Economist article on coronavirus

R is a reference to R0, otherwise known as the basic reproductive rate, and means the number of new cases from a single patient infection. R0 has to be above 1 for a disease to persist. It is a ...
M__'s user avatar
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4 votes

Economist article on coronavirus

R, the reproductive number, relates to the average number of (new) people that will get sick (infected) per person that is already sick. For instance, if $R=2$ and you start with a single infected ...
Sextus Empiricus's user avatar
4 votes
Accepted

Calculating the mortality rate of a pandemic, e.g. coronavirus 2019-nCov?

This may not strike most as a bioinformatics, but getting the key clinical outcome is essential in understanding the molecular basis of pathogenicity. I think the mortality rate is over-reported. ...
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2 votes

Calculating the mortality rate of a pandemic, e.g. coronavirus 2019-nCov?

I was facing this problem in January when coming up with a methodology to forecast on the UrbanSurvival.com site. My solution - using low data collection was to use a daily rolling rate of infections ...
George Ure's user avatar
2 votes

Calculating the mortality rate of a pandemic, e.g. coronavirus 2019-nCov?

To add to Michael G.'s answer, there is a further wrinkle in the case of 2019-nCov that is due to the exponential growth in confirmed infections daily. That growth affects your second formula ...
alizabr's user avatar
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2 votes
Accepted

Prediction model for spread of coronavirus

The original R0 calculation was developed in the early 1900s to model malaria transmission and is known as the Ross-MacDonald model so your idea is over 100 years old. The model was very famous for ...
M__'s user avatar
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1 vote

Statistical approach to link DNA methylation with toxic element exposure and health outcome

Having given some thought to this, I'd still use machine learning. I would attempt to augment the negative controls however. Is there a suitable published data set? R program is caret but it high ...
M__'s user avatar
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