New answers tagged

0 votes

Identifying somatic mutations in cell lines

I am not actively following this field, so take my answer with a grain of salt. With bulk data, you can't easily tell how subclones differ from each other or characterize the mutation rates in ...
  • 6,130
1 vote

Transcript vs Primary transcript on phytozome

According to a team lead at Phytozome: Multi-exon genes can produce different transcripts via process of alternative splicing:  inclusion/exclusion of particular exons in the spliced transcript....
  • 107
2 votes

Inconsistent replicate numbers in RNA-seq

It will not do any harm other than a reduction in statistical power compared to more samples per group. Common analysis tools such as DESeq2, edgeR and limma will work on unequal sample size just fine....
  • 373

Top 50 recent answers are included