4
votes
Strategy for merging many VCFs
We created this over the pandemic when we needed to merge loads of VCFs which all have the same header and first few columns (ie same variants)
https://github.com/iqbal-lab-org/ivcfmerge
That page ...
- 41
3
votes
Strategy for merging many VCFs
I ended up using an iterative approach (inspired by this post), which took 1.5 hours - so a massive speed up (and that was just the sequential version).
Note: fd is ...
- 663
3
votes
Accepted
Merging multiple seurat datalist together
The first parameter of merge should be a Seurat object, the second (y) can be one Seurat object or a list of several. Try:
...
- 252
2
votes
Accepted
2
votes
Merging multiple seurat datalist together
You should be able to use something like this:
Reduce(
f = function(x, y) {merge(x, y, merge.data = FALSE)},
x = datasets # list of Seurat objects
)
This ...
- 3,892
1
vote
Strategy for merging many VCFs
Perform a tree based merge of the files.
Sort the files into groups that can easily be merged in a measurable amount of time.
Merge each group into a separate Variant Call Format (VCF) file
Has the ...
- 111
1
vote
Merge data frame on either of the 2 columns in R or python
I think this question is more about subsetting than merging. You can try this solution in R:
...
- 313
1
vote
Accepted
Large amount of REF prefix differences after lifting
It is important that after lifting over a VCF/BCF file from one coordinate system to another, the header of the resulting file contains the chromosome/contig names as present in the coordinate system ...
- 750
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