2 votes

Methylation data: beta values are normally distributed

$\beta$ values are the ratio of methylated to unmethylated probe intensities. This means that $\beta \in [0, 1]$, so it can't be normally distributed, by definition. Its distribution may have sections ...
  • 1,254
1 vote

dog coordinates (canFam3) to human coordinates (hg19)

Based on this old answer, this is not recommended for liftOver. For between-species liftovers, it is claimed that you are likely to want a different tool such as pslMap. For a lot of rather detailed ...

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