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Why can't AlphaFold predict the consequences of point-mutations?
Other have addressed why AlphaFold2 cannot really get the necessary signal from MSA (Multiple Sequence Alignment) and memory to properly model a variant, but I thought I'd add my observations/rants.
I ...
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Would duplicate climatic variables impact maxent?
Ok I understand better now so I'll write an answer.
Look at the bioclimatic data site. You can download them from the main page, but the suggestion to generate them from the time series data using an ...
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Why can't AlphaFold predict the consequences of point-mutations?
As marcin points out in the comments: by "AphaFold (AF) has not been trained to predict structural consequences of point mutations" it is meant "AF is not able to tell you whether your ...
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Why can't AlphaFold predict the consequences of point-mutations?
This answer is from common knowledge rather than specific infield expertise. The question could be more expertly answered by other members.
If you really want to pursue this type of calculation, it's ...
M__♦
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