New answers tagged normalization
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Normalization methods to combine scRNA-seq experiments with different sequencing depths
Coincidentally, a recent preprint out of Lior Pacther's lab covers some of these details around scRNA-seq depth normalization.
They find that a "PFlog1pPF" normalization method is able to ...
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What is the difference between Normalized Expression in EdgeR vs DESeq2?
First, and most obviously, two independent methods will never fully agree.
Second, while the DESeq2-related code in fact gets the normalized counts based on the size factors the edgeR/voom code ...
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