4 votes
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What are values of FILTER column of vcf files produced by Mutect2

You haven't told us what commands you ran, so I am assuming you first ran Mutect2 and then FilterMutectCalls. If so, the ...
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2 votes
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How to introduce point mutations in a protein structure?

PDBFixer and pyMutate are simple, lightweight, free and open-source. Both don't do any optimizing, though, so you may have to run some molecular dynamics afterward to get what would be the right "...
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