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Oct 8, 2020 at 10:59 comment added M__ Okay you need to do this via a Q-Q plot, or at least it is one way to do this. The an alternative is to minimise the residual. When I get a chance I'll post an explanation. You don't necessarily need to transform, it depends on the 'diagnostics', e.g. Q-Q.
Oct 8, 2020 at 10:47 comment added snowflake Yes it's general linear modelling (written in the first sentence).
Oct 8, 2020 at 10:06 comment added M__ Normalisation is standard procedure for GLM
Oct 8, 2020 at 10:02 comment added M__ Please could you clarify if by "GWAS analysis" you are referring to general linear modelling (GLM)? This is regression analysis assessed using regression weights and a residual to understand the association between alleles and phenotypes. Is that correct?
Oct 7, 2020 at 8:29 history asked snowflake CC BY-SA 4.0