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Let's say I want to retrieve the yeast-specific identifier for a certain protein, in the example below it will be P00330 which I would like to link to YOL086C.

When I go to uniprot's sparql UI and type

PREFIX up:<http://purl.uniprot.org/core/> 
PREFIX rdfs:<http://www.w3.org/2000/01/rdf-schema#> 

SELECT *
WHERE
{
    Bind(<http://purl.uniprot.org/uniprot/P00330> as ?protein).
    ?protein rdfs:seeAlso ?db .
    ?db up:database <http://purl.uniprot.org/database/SGD> .

}

it returns

protein db
http://purl.uniprot.org/uniprot/P00330  http://purl.uniprot.org/sgd/S000005446

How would I now go on and find the YOL086C? When I add the line

?db ?p ?o

to the query above, I don't see anything that would directly lead me to the identifier.

I also tried to access another database

?db2 up:database <http://purl.uniprot.org/database/EuPathDB>

but this returns all kind of databases while I am interested only in the FungiDB. How could I select this one?

How could I link the two IDs to each other?

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1 Answer 1

4
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Ok, figured it out by looking at the scheme uniprot provides:

PREFIX up:<http://purl.uniprot.org/core/> 

SELECT ?protein ?yeast_id
WHERE
{
    Bind(<http://purl.uniprot.org/uniprot/P00330> as ?protein).
    ?protein up:encodedBy ?gene .
    ?gene up:locusName ?yeast_id    
}

So one starts at the accession number in the middle and then uses the path to the actual locusName.

Also the path via the database works fine, I just did not use the seeAlso correctly (protein was only bound to db but not to db2, that's why it returned all entries):

PREFIX up:<http://purl.uniprot.org/core/> 
PREFIX rdfs:<http://www.w3.org/2000/01/rdf-schema#> 

SELECT ?protein ?db ?db2
WHERE
{
    Bind(<http://purl.uniprot.org/uniprot/P00330> as ?protein).
    ?protein rdfs:seeAlso ?db .
    ?protein rdfs:seeAlso ?db2 .
    ?db up:database <http://purl.uniprot.org/database/SGD> .
    ?db2 up:database <http://purl.uniprot.org/database/EuPathDB>

}

This will return the desired output (one would still have to process the db2 entry, of course):

protein db  db2
http://purl.uniprot.org/uniprot/P00330  http://purl.uniprot.org/sgd/S000005446  http://purl.uniprot.org/eupathdb/FungiDB:YOL086C
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2
  • $\begingroup$ I am really happy to see you found your answer! Could we use this as an example query on the sparql endpoint itself? $\endgroup$
    – Jerven
    Commented Mar 13, 2018 at 13:45
  • 1
    $\begingroup$ @Jerven: feel free to use it, sure! I just updated my answer to show that also the path via the database works fine; I just used it wrong. $\endgroup$
    – Cleb
    Commented Mar 13, 2018 at 14:02

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