From the preprint published by 1000 genome project (https://www.biorxiv.org/content/10.1101/2021.02.06.430068v1.full) I think the 30x data is for WGS. Can anyone confirm for me if the following file is really WGS data? ftp://ftp.sra.ebi.ac.uk/vol1/run/ERR324/ERR3242643/HG03007.final.cram.
Also, Is there any more freely available sequencing data where I can find WGS data for 30x and low coverage(<10x) for the same sample for the South Asian population?


1 Answer 1


Yes, those are the .cram files for the 30x whole genome sequencing data for 1000 genomes.

If you want 10x and 30x sequence data for the same individual, you can just downsample the 30x .cram file using samtools view -s.

  • $\begingroup$ 30x WGS or WES? Can u specify it in your answer? $\endgroup$ Sep 9, 2022 at 14:17
  • $\begingroup$ WGS - I don't know why you'd think it was exome sequencing - there's no mention of that in the paper or the website. $\endgroup$
    – user438383
    Sep 9, 2022 at 14:22
  • $\begingroup$ There is actually. But that was at the depth of 65.7x coverage. However, I asked just to be sure, anyway once again thanks for your answer. $\endgroup$ Sep 9, 2022 at 14:27

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service and acknowledge that you have read and understand our privacy policy and code of conduct.

Not the answer you're looking for? Browse other questions tagged or ask your own question.