I'd like to do a targeted screening analysis for trace contaminates. However, due to the nature of the sample preparations, the retention times I'm getting drift a lot from run to run and XCMS isn't properly identifying my standards and thus affecting my ability to evaluate my samples.
Is there some trick to getting XCMS to identify the proper retention time that I'm missing?
Is there some other software I should be using? (We have several different instruments from different vendors so it's better if it's not tied to the particular MS)