How can I find ligands of receptors (or vice versa)?
For example, I want to find the receptors of IL-8 (CXCL8).
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3 Answers
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CellPhoneDB is a publicly available repository of curated receptors, ligands and their interactions.
The interactions can be searched or downloaded.
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Have you tried STRING?
It's a publicly available protein-protein interaction database, so it won't be a complete picture.
Ingenuity Pathways Analysis (IPA) is really nice but is a paid service. Ask your institution if they have a license for one.
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$\begingroup$ Can you include a link to IPA please. $\endgroup$ Commented Oct 22, 2018 at 13:43
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$\begingroup$ qiagenbioinformatics.com/products/ingenuity-pathway-analysis $\endgroup$ Commented Oct 22, 2018 at 17:47
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CellTalkDB is another option for a searchable ligand-receptor database. According to the webpage it is curated from other databases and the literature. Details are available in the publication.
