2 votes

WGBS vs ONT, which one should I trust?

Methylation can be cell-specific, which makes it difficult to evaluate accuracy on a bulk-cell level (even within the same tissue). How can you tell that the differences you're seeing are due to ...
  • 12.5k
1 vote

WGBS vs ONT, which one should I trust?

I would assess directionality and accuracy of prediction by 1) WGBS predicting ONT and then 2) ONT predicting WGBS. Firstly, I would use deep learning (or machine learning) and train WGBS against ONT, ...
  • 9,149

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