2
votes
obtaining a fragment data file bed from bam
There's an example in the README (https://github.com/epifluidlab/cragr#example-datasets):
For you information, below are steps from the BAM file to the
fragment file:
...
- 695
2
votes
WGBS vs ONT, which one should I trust?
Methylation can be cell-specific, which makes it difficult to evaluate accuracy on a bulk-cell level (even within the same tissue). How can you tell that the differences you're seeing are due to ...
- 13.8k
1
vote
Mendelian randomization
I understand linkage disequilibrium (LD) versus panmixia, which the technical term for Mendelian randomisation and for humans PLINK is a population package. The best outcome is a correlation between ...
M__♦
- 11.9k
1
vote
WGBS vs ONT, which one should I trust?
I would assess directionality and accuracy of prediction by 1) WGBS predicting ONT and then 2) ONT predicting WGBS.
Firstly, I would use deep learning (or machine learning) and train WGBS against ONT, ...
M__♦
- 11.9k
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